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Abstract - Original Article
| J Cerebrovasc Endovasc Neurosurg. 2022 24(2): 144-153 ¨Ï The Journal of Cerebrovascular and Endovascular Neurosurgery |
 
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| Comparison of transarterial n-BCA and Onyx embolization of brain arteriovenous malformations: A single-center 18-year retrospective analysis |
| Faraz Behzadi1, Daniel M Heiferman2, Amy Wozniak3, Benjamin Africk4, Matthew Ballard1, Joshua Chazaro1, Brandon Zsigray5, Matthew Reynolds5, Douglas E Anderson5, Joseph C Serrone5 |
| 1Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA 2Semmes-Murphey Clinic, Memphis, TN, USA 3Clinical Research Office, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA 4Department of Pediatric Neurology, Stanford University School of Medicine, Palo Alto, CA, USA 5Department of Neurological Surgery, Stritch School of Medicine, Loyola University Medical Center, Maywood, IL, USA |
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| Objective: Brain arteriovenous malformations (AVM) are commonly treated with endovascular embolization. Due to the rapid evolution of endovascular technology and lack of consistent practice guidelines regarding AVM embolization, further study of AVM embolization outcomes is warranted.
Methods: We conducted a retrospective review of AVMs embolized at a single center from 2002-2019. Patient demographics, AVM characteristics, intention of embolization, and angiographic and clinical outcome after embolization were recorded. We compared the embolization results of those treated with n-butyl cyanoacrylate (n-BCA) and Onyx.
Results: Over an 18-year period at our institution, 30 (33%) of 92 AVMs were treated with embolization. n-BCA was used in 12 cases and Onyx in 18 cases. Eighty-seven pedicles were embolized over 47 embolization sessions. Fifty percent of AVMs treated with n-BCA underwent more than one embolization session compared to 22% when Onyx was used. The median total percent volume reduction in the n-BCA AVMs was 52% compared to 51% in Onyx AVMs. There were 2 periprocedural complications in the n-BCA cohort and none in the Onyx cohort.
Conclusions: In this small retrospective series, Onyx and n-BCA achieved similar occlusion results, although n-BCA required more sessions and pedicles embolized to do so. |
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| Key words : Arteriovenous malformation, Embolization, n-butyl cyanacrylate (n-BCA), Ethylene vinyl alcohol copolymer, Onyx |
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